Cardiology and Angiology: An International Journal <p style="text-align: justify;"><strong>Cardiology and Angiology: An International Journal (2347-520X)</strong>&nbsp;aims to publish high quality papers (<a href="/index.php/CA/general-guideline-for-authors">Click here for Types of paper</a>) in all areas of ‘Cardiology and Angiology research’. The journal also encourages the submission of useful reports of negative results. This is a quality controlled,&nbsp;OPEN&nbsp;peer reviewed, open access INTERNATIONAL journal.</p> SCIENCEDOMAIN international en-US Cardiology and Angiology: An International Journal 2347-520X Intraoperative Hypertensive Crisis in a Patient with Normotensive Primary Aldosteronism. Lessons from a Clinical Case <p>Primary hyperaldosteronism is the most frequent cause of secondary hypertension. However, it can also be found in apparently normotensive patients, often associated with recurrent hypokalemia and isolated hypertensive episodes.</p> <p>We hereby present the case of a normotensive 50-year-old female patient with a surgical left kidney mass; however, after anaesthetic induction, surgery was aborted due to a severe hypertensive crisis. She was referred to our Hypertension Outpatient Clinic to rule out pheochromocytoma/ paraganglioma. The anamnesis revealed unexplained episodes of hypokalemia. Ambulatory blood pressure monitoring showed normal mean values of blood pressure and heart rate, with an isolated hypertensive peak. Plasma glucose, ions, creatinine, lipids, metanephrines and chromogranin A were normal, but plasma aldosterone was clearly elevated with suppressed plasma renin activity and high aldosterone/renin activity ratio. Primary aldosteronism was confirmed by the captopril test. Abdominal CT was compatible with left adrenal hyperplasia. Treatment with low-dose spironolactone was well tolerated and resulted in normal blood pressure, normokalemia and unsuppressed plasma renin activity. The patient underwent successful laparoscopic removal of a renal oncocytoma.&nbsp;</p> <p>We conclude that normotensive primary aldosteronism is not harmless; it can be associated with severe hypokalemia, anxiety, depression, hypertensive crisis and cardiovascular damage. Patients can also develop resistant hypertension. Adequate treatment can decisively improve the survival and quality of life of the patients with primary aldosteronism, but a correct diagnosis is needed first. Therefore, it must be considered as a diagnostic possibility in normotensive patients with unexplained hypokalemia or isolated hypertensive episodes.</p> Agnieszka Kuzior Manuel Esteban Nivelo-Rivadeneira Paula Fernandez-Trujillo-Comenge Esperanza Perdomo-Herrera Alba Lucia Tocino-Hernandez Marta Martin-Perez Paula Gonzalez-Diaz Maria Victoria Sainz de Aja-Curbelo Ana Delia Santana-Suarez Francisco Javier Martinez-Martin ##submission.copyrightStatement## 2019-07-06 2019-07-06 1 7 10.9734/ca/2019/v8i430107 Unmasking Brugada Syndrome with Oral Flecainide Provocation. A Case Series of Three Patients <p>The present case series discuss three patients who had brugada type 2/ type 3 like ECG pattern that was converted to type 1 pattern with oral flecanide challenge test. Brugada syndrome is associated with a high incidence of sudden cardiac death,&nbsp;&nbsp; typical ECG pattern being ST-segment elevation in the right precordial leads with T wave inversion. Pharmacological provocation should only be performed when the baseline ECG is not diagnostic of Brugada Syndrome. PR prolongation in the baseline ECG is also a contraindication because of the risk of inducing AV block. Drug challenge is performed under strict monitoring of BP and 12-lead ECG and facilities for cardio version and resuscitation are available. Atypical RBBB pattern/type 2/3 Brugada pattern on ECG in patients of syncope or family history of sudden cardiac arrest is commonly encountered by a cardiologist. This can be performed to provoke type 1 brugada pattern on ECG. Diagnosed cases of Brugada may be treated with ICD with proper indication if needed and thus prevent sudden cardiac death.</p> R. Singla A. Udyavar A. Gupta A. Bade K. Munde N. O. Bansal ##submission.copyrightStatement## 2019-07-16 2019-07-16 1 6 10.9734/ca/2019/v8i430108 Risk Factors of Cardiovascular Disease among Ghanaian Police Officers <p><strong>Background:</strong> Cardiovascular diseases continue to be a global public health burden among occupational groups like Police officers. Police officers play important roles to ensure law and order in countries. However, the nature of police work exposes them to violence and stress. Again, irregular food habits, irregular exercise, inadequate sleep, smoking and drinking are lifestyles which makes police officers prone to high incidence of cardiovascular disease (CVD).</p> <p><strong>Aim:</strong> This study looked at the prevalence of CVD risk factors among police officers in Kumasi, Ghana.</p> <p><strong>Study Design:</strong> Cross- sectional.</p> <p>Place and Duration of study: Ashanti Regional Police Headquarters, Kumasi, Ghana, between September, 2017 to July, 2018.</p> <p><strong>Methodology:</strong> Weight, height, Body Mass Index (BMI), waist circumference, lipid profile, systolic and diastolic blood pressure of 120 officers were measured. Additionally, lifestyle and dietary factors such as exercise and intake of fruits of Police officers were assessed. Data were analyzed by SPSS version 22.0.</p> <p><strong>Results:</strong> Slightly more than half (63, 52.5%) of the officers were females and the remaining (57,47.5%) were males. The mean of the various CVD risk factors among the total study participants are as follows; BMI 28.184±4.461 kg/m<sup>2</sup>, waist circumference 92.702±10.941 cm, systolic blood pressure (SBP) 128.121±17.047 mmHg, diastolic blood pressure (DBP) 85.569±10.854 mmHg, fasting blood sugar 5.387±1.756 mmol/l, high density lipoprotein (HDL) 1.546±0.211 mmol/l, low density lipoprotein 2.321±0.706 mmol/l (LDL) and total cholesterol (TC) 4.362±0.906 mmol/L.&nbsp; Prevalence of obesity among male and female officers were 43.9% and 36.5% respectively. With regards to hypertension, policemen and women recorded 31.6% and 20.6% respectively and dyslipidemia among males and females were 43.9% and 85.7% respectively.</p> <p>Conclusion: The officers were generally overweight, with over a quarter having hypertension and about two-thirds having dyslipidemia, making their risk for CVDs high. Further studies to elucidate the causes are required, routine medical screening and nutritional support are recommended.</p> Miriam Essien Herman Erick Lutterodt Reginald Adjetey Annan ##submission.copyrightStatement## 2019-09-09 2019-09-09 1 9 10.9734/ca/2019/v8i430109