CHA2DS2-VASc-HSF Score as a Predictor of Severity of Coronary Artery Disease in Patients Undergoing Coronary Angiography
Cardiology and Angiology: An International Journal,
Background: Cardiovascular atherosclerosis, particularly coronary artery disease (CAD), represents the main reason for death prematurely over the world. Risk stratification and prevention by risk factor modification are crucial aspects of CAD therapy. The CHADS2 and CHA2DS2-VASc scores are effective in determining the risk of thrombosis in non-valvular atrial fibrillation (AF). The current research aimed to determine the CHA2 DS2-VASc-HSF score as a predictor for CAD severity in CAD patients after coronary angiography.
Methods: This cross-sectional study was assessed on 100 patients who attended the coronary care unit and underwent coronary angiography. They were categorised into three groups: Group I: Low syntax scores (2-13), Group II: Intermediate syntax score (14-20), and Group III: High syntax score (21-40).
Results: Our study showed that the SYNTAX score revealed a statistically significant relation with patient's age, gender, and presentation. Regarding the medical history of the studied participant in relation to SYNTAX score, most patients reported a history of HTN, DM, Dyslipidemia, CHF, and previous history of vascular disease showed intermediate and high SYNTAX score in comparison to those with normal blood pressure, glucose level, lipid profile, no CHF history and those no previous history. SYNTAX score showed significant relation with ejection fraction and CHA2 DS2-VASc-HSF score of the patient. Significant low ejection fraction in high SYNTAX score patients compared to low SYNTAX score patients. Significant high average of CHA2 DS2-VASc-HSF score among those with high and intermediate SYNTAX score compared to those with low SYNTAX score.
Conclusions: CHA2DS2-VASc-HSF should be constituted as the ideal scoring scheme for predicting the severity of CAD. Risk scoring systems may be effective as predictors due to their simplicity and easy employment by physicians in ordinary practice without incurring additional costs.
- CHA2DS2-VASc-HSF score
- coronary artery disease
- coronary angiography
How to Cite
Sihag BK, Jain D, Subramanian GJJoC, Research D. Comparative Study of Scores for Prediction of Coronary Artery Disease Severity: Evaluation of a Newly Formulated CHA2DS2-VASc-HSLp (a) Score. 2018;12.
Taşolar H, Çetin M, Ballı M, Bayramoğlu A, Otlu YÖ, Türkmen S, et al. CHA2DS2-VASc-HS score in non-ST elevation acute coronary syndrome patients: assessment of coronary artery disease severity and complexity and comparison to other scoring systems in the prediction of in-hospital major adverse cardiovascular events. 2016;16:742.
Hsieh MJ, Lee CH, Chen CC, Chang SH, Wang CY, Hsieh I-CJJoc. Predictive performance of HAS-BLED risk score for long-term survival in patients with non-ST elevated myocardial infarction without atrial fibrillation. 2017;69:136-43.
Collet C, Onuma Y, Miyazaki Y, Morel M-A, Serruys PWJCd, therapy. Integration of non-invasive functional assessments with anatomical risk stratification in complex coronary artery disease: the non-invasive functional SYNTAX score. 2017;7:151.
Ji H, Li Y, Fan Z, Zuo B, Jian X, Li L, et al. Monocyte/lymphocyte ratio predicts the severity of coronary artery disease: a syntax score assessment. 2017;17:90.
Graves KG, May HT, Jacobs V, Knowlton KU, Muhlestein JB, Lappe DL, et al. CHA2DS2-VASc scores and Intermountain Mortality Risk Scores for the joint risk stratification of dementia among patients with atrial fibrillation. 2019;16:3-9.
Patti G, Sticchi A, Pasceri V, Ricci F, Renda G, Hamrefors V, et al. Co-predictive role of the CHA2 DS2-VASc score for stroke, coronary events and mortality in diabetic patients without atrial fibrillation. 2019;35:e3145.
Hsieh CY, Lee CH, Wu DP, Sung SFJA. Prediction of new-onset atrial fibrillation after first-ever ischemic stroke: a comparison of Chads2, CHA2DS2-VASc and HATCH scores and the added value of stroke severity. 2018;272:73-9.
Ciftci O, Yilmaz KC, Karacaglar E, Yilmaz M, Ozin B, Muderrisoglu IHJTEjom. The Novel CHA2DS2-VASC-FSH Score is Predictive of Severe Coronary Artery Disease on Coronary Angiography in Patients with Atrial Fibrillation and Unstable Symptoms. 2019;51:165.
Bala P, Rahman A, Ullah M, Haque MM, Alam K, Rahman MA, et al. Association of CHA2DS2-VASc-HS Score with Adverse In-hospital Outcomes in Patients with Non-ST Segment Elevation Myocardial Infarction. 2019;11:159-66.
Kurtul A, Yarlioglues M, Duran MJTAjoc. Predictive value of CHA2DS2-VASC score for contrast-induced nephropathy after percutaneous coronary intervention for acute coronary syndrome. 2017;119:819-25.
Ritchie ME, Phipson B, Wu DI, Hu Y, Law CW, Shi W, Smyth GK. limma powers differential expression analyses for RNA-sequencing and microarray studies. Nucleic acids research. 2015 Apr 20;43(7):e47.
Karabuva S, Carević V, Radić M, Fabijanić D. The association of ABO blood groups with extent of coronary atherosclerosis in Croatian patients suffering from chronic coronary artery disease. Biochemia medica. 2013 Oct 15;23(3):351-9.
Association AD. Diagnosis and classification of diabetes mellitus. Diabetes care. 2014;37:S81-S90.
Diagnosis and classification of diabetes mellitus. Diabetes Care. 2014;37 Suppl 1:S81-90.
Killip T, 3rd, Kimball JT. Treatment of myocardial infarction in a coronary care unit. A two year experience with 250 patients. Am J Cardiol. 1967;20:457-64.
Killip T, Kimball JT. Treatment of myocardial infarction in a coronary care unit: a two year experience with 250 patients. American Journal of Cardiology. 1967;20:457-64.
Lang RM, Badano LP, Mor-Avi V, Afilalo J, Armstrong A, Ernande L, Flachskampf FA, Foster E, Goldstein SA, Kuznetsova T, Lancellotti P. Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. European Heart Journal-Cardiovascular Imaging. 2015;16(3):233-271.
Lang T, Heasman M. Food wars: the global battle for mouths, minds and markets. Routledge; 2015b.
Appleton CP, Jensen JL, Hatle LK, Oh JK. Doppler evaluation of left and right ventricular diastolic function: a technical guide for obtaining optimal flow velocity recordings. J Am Soc Echocardiogr. 1997;10:271-92.
Ralapanawa U, Sivakanesan R. Epidemiology and the Magnitude of Coronary Artery Disease and Acute Coronary Syndrome: A Narrative Review. J Epidemiol Glob Health; 2021.
Karabağ Y, Çağdaş M, Rencuzogullari I, Karakoyun S, Artaç İ, İliş D, et al. Relationship between C‐reactive protein/albumin ratio and coronary artery disease severity in patients with stable angina pectoris. Journal of clinical laboratory analysis. 2018;32:e22457.
Modi R. TCTAP A-043 CHA2DS2-VASc-HSF Score: New Predictor of Severity of Coronary Artery Disease in 2,976 Patients. Journal of the American College of Cardiology. 2019;73:S22-S.
Andrianto A, Jovie B, Al Farabi MJ, Gandi P, Shonafi KA, Lathifah R. Novel CHA2DS2-VASc-HSF is Superior to CHADS2 and CHA2DS2-VASc Score to Predict the Risk of Severe Coronary Artery Disease. 2020.
Cetin M, Cakici M, Zencir C, Tasolar H, Baysal E, Balli M, et al. Prediction of coronary artery disease severity using CHADS2 and CHA2DS2-VASc scores and a newly defined CHA2DS2-VASc-HS score. The American Journal of Cardiology. 2014;113:950-6.
Ciftci O, Yilmaz KC, Karacaglar E, Yilmaz M, Ozin B, Muderrisoglu IH. The Novel CHA2DS2-VASC-FSH Score is Predictive of Severe Coronary Artery Disease on Coronary Angiography in Patients with Atrial Fibrillation and Unstable Symptoms. The Eurasian Journal of Medicine. 2019;51:165.
Zhang QY, Ma SM, Sun JY. New CHA 2 DS 2-VASc-HSF score predicts the no-reflow phenomenon after primary percutaneous coronary intervention in patients with ST-segment elevation myocardial infarction. BMC Cardiovascular Disorders. 2020;20:1-9.
Al-Shorbagy AN, Al-Cekelly MM, Dwedar AA-s, Soliman MH. The Predictive Value of Newly Defined CHA2DS2-VASC-HSF Score for Severity of Coronary Artery Disease in Non ST Segment Elevation Myocardial Infarction. Zagazig University Medical Journal. 2018;24:289-96.
Uysal OK, Turkoglu C, Duran M, Kaya MG, Sahin DY, Gur M, et al. Predictive value of newly defined CHA2DS2-VASc-HSF score for severity of coronary artery disease in ST segment elevation myocardial infarction. Kardiol Pol. 2016; 74:954-60.
Modi R, Patted SV, Halkati PC, Porwal S, Ambar S, Mr P, et al. CHA2DS2-VASc-HSF score – New predictor of severity of coronary artery disease in 2976 patients. International Journal of Cardiology. 2017; 228:1002-6.
Abstract View: 24 times
PDF Download: 8 times