Highly Sensitive C Reactive Protein as a Predictor of in Hospital Outcome in Patients with Acute Coronary Syndrome
Amr Hamama Hussen
Cardiovascular Medicine Department, Faculty of Medicine, Tanta University, Tanta, Egypt.
Ahmed Farok Alaraag
Cardiovascular Medicine Department, Faculty of Medicine, Tanta University, Tanta, Egypt.
Mohamed Ahmed Abdalaal
Cardiovascular Medicine Department, Faculty of Medicine, Tanta University, Tanta, Egypt.
Ayman Mohamed Alsaed
Cardiovascular Medicine Department, Faculty of Medicine, Tanta University, Tanta, Egypt.
*Author to whom correspondence should be addressed.
Abstract
Background: C-reactive (CRP) protein is a well-studied inflammatory factor whose prognostic value in cardiovascular diseases in recent years has become increasingly important. Assesses of prognostic value of highly sensitive C-reactive protein (hs-CRP) in patients with acute coronary syndrome (ACS) wasthe aim of this work.
Methods: This observational research was conducted on 50 individuals had ACS admitted to CCU and indicated for invasive coronary angiography. Cases were classified in 2 groups depending on the level of hs-CRP: group A included (14) cases with hs-CRP > (2) and group B involved (36) cases with hs-CRP ≥ (2). All patients were subjected to: laboratory investigations (creatinine, urea, aspartate aminotransferase (AST), alanine amino transferase (ALT), troponin, creatine kinase myocardial band (CKMB), hs-CRP, HbA1C, lipid profile, twelve lead surface ECG, echocardiography and coronary angiography.
Results: Total cholesterol, LDL, HDL and triglyceride were significantly higher in group B compared to group A(P=0.001). Stent implantation was significantly higher in group 2 compared to group 1 (P=0.040)
Conclusions: There were correlation between hs CRP and lipid profile as a risk factor and there was no correlation between in hospital outcome and hs CRP in ACS patients due to small sized study.
Keywords: Highly sensitive, c reactive protein, hospital outcome, acute coronary syndrome