Speckle Tracking in Acute Non-St Elevation Acute Coronary Syndromes Patients as a Factor of Risk Stratification
Ahmed Sobhy Elnemr
Cardiology Department, Faculty of Medicine, Tanta University, Tanta, Egypt.
Aliaa Elsayed Shaaban
Cardiology Department, Faculty of Medicine, Tanta University, Tanta, Egypt.
Suzan Bayoumy El-Hefnawy
Cardiology Department, Faculty of Medicine, Tanta University, Tanta, Egypt.
Samia Mahmoud Sharaf Eldein
Cardiology Department, Faculty of Medicine, Tanta University, Tanta, Egypt.
*Author to whom correspondence should be addressed.
Abstract
Background: Coronary artery disease (CAD) early diagnosis remains a clinical problem in patients with non-ST elevation acute coronary syndrome (NSTE-ACS), especially in the regional wall motion abnormalities’ absence on presentation by Echo. This study assessed the relationship between ECG changes and speckle Tracking in subjects with acute NSTE-ACS.
Methods: This prospective trial was performed on 100 subjects with NSTE-ACS. All subjects were subjected to laboratory tests [complete blood picture, renal function test, liver test profile, lipid profile, RBS and cardiac biomarkers (cardiac troponin, creatinine kinase and CK-MB)], 12 lead ECG, Echocardiography (TTE, speckle tracking), Image analysis and coronary angiography.
Results: regarding IVRT, TDI e`, TDI a`, a considerable difference between the two groups were found. DBP was considerably lower in STD group in comparison with TWI group (P value= 0.047). IVRT, TDI a` and GLS were considerably higher in STD group in comparison with TWI group (P value= 0.024, 0.031, 0.003 respectively).
Conclusions: Speckle tracking could be used as part of standard echo for the examination of individuals suffering from NSTE-ACS.
Keywords: Speckle tracking echocardiography, non-St elevation, acute coronary syndromes, risk stratification