Kunyima Relations Establishment on SS Sickle Cell Anaemia Women Investigation in Democratic Republic of Congo
A. B. Kunyima *
Department of Chemistry, Laboratory of Physical Organic and Food Chemistry (LACOPA), Faculty of Sciences, University of Kinshasa, P.O.Box 190 Kinshasa XI, Democratic Republic of Congo
S. N. Lusamba
Department of Chemistry, Laboratory of Physical Organic and Food Chemistry (LACOPA), Faculty of Sciences, University of Kinshasa, P.O.Box 190 Kinshasa XI, Democratic Republic of Congo and Department of Chemistry, Laboratory of Analytical Chemistry and Quality Control, Faculty of Sciences, University of Kinshasa, P.O.Box 190 Kinshasa XI, Democratic Republic of Congo
M. B. Kunyima
Higher Institute of Medical Techniques of Kinshasa, P.O.Box 774 Kinshasa XI, Democratic Republic of Congo
*Author to whom correspondence should be addressed.
Abstract
Background: The sickle cell anaemia is a genetics sickness, autosomal, recessive, secondary to a punctual mutation at sixth codon level of globine gene with substitution of glutamic acid by valine. The prevalence of S hemoglobin is relatively high, reaching 40 % of central Africa population.
Aim and objective: The overall purpose of this paper is to show that the cardiac exergetic yield depends only on differential pressure while is greatly depending on cardiac frequency.
Methodology: The sickle cell anaemia persons were the target population. The experiments have been performed in Centre of Mixte Medicine and SS anaemia in Kinshasa (DRC) called Centre MABANGA. The blood pressure measurements and calculations are our methodology of work. The calculations have been done individually on the sample of 82 females whose the age varies between 13-57 years. The figures have been plotted by means of Origin 8 program. The Visio 2010 software was used for equations.
Results: The investigation on sickle cell anaemia women allowed to establish the relations between cardiac exergetic yield ( ) and differential pressure ( ) called KUNYIMA Relations from the name of Dr. KUNYIMA BADIBANGA Anaclet, the designer of this research project. The sickle cell population under medical treatment exhibited in general very weak cardiac yield. Details in this paper show the linear dependence of cardiac yield on differential pressure as well for healthy persons as for sickle cell persons evidencing this ancient hypothesis according which the healthy person cardiac yield in the healthy environment remains constant (because is constant). The difference between the healthy persons and sick persons resides in the slopes of straight lines.
Conclusion: So all biological system which is not in transient state works at constant cardiac yield. Also KUNYIMA Equation and KUNYIMA Formula have been successfully verified. An outstanding fact should be branded on memory: differential enthalpy is the total enthalpy accompanying the blood in its motion. With this paper the content of Physical Cardiochemistry as a research field is forthcoming and becomes a burning desire.
Keywords: Kunyima Equation, Kunyima Formula, Kunyima Chart, Volumic density of differential enthalpy, Exergetic cardiac yield, Physical Cardiochemistry