Relationship between Aortic Root Diameter and Type 2 Diabetes in Hypertensive Patients
Ahmed Mohamed Elhosary
Cardiovascular Medicine Department, Faculty of Medicine, Tanta University, Tanta, Egypt.
Amany Mohamed Allaithy
Cardiovascular Medicine Department, Faculty of Medicine, Tanta University, Tanta, Egypt.
Mohamed Ahmed Abd-alaal
Cardiovascular Medicine Department, Faculty of Medicine, Tanta University, Tanta, Egypt.
Hanan Kamel Kassem
Cardiovascular Medicine Department, Faculty of Medicine, Tanta University, Tanta, Egypt.
*Author to whom correspondence should be addressed.
Abstract
Background: Diabetes mellitus (DM) involves a series of metabolic conditions associated with hyperglycaemia which is caused by defects in insulin secretion and./or insulin action. The aim of this work was assessment of the relationship between Aortic Root (AOR) diameter and type 2 diabetes mellitus (T2DM) in Hypertension (HTN) cases.
Methods: This prospective case control study was carried out on 80 HTN cases. Cases were divided in to three groups: Group A (30 HTN cases) with type 2 DM with good metabolic control (Hb AIC ≤ 7.0), group B: (30 HTN cases) with type 2 DM with poor metabolic control (Hb AIC > 7.0) and C (Control group) 20 HTN, non-DM subjects of the same age and sex group with no other comorbid conditions.
Results: FS had a significant decline in group A (P2 = 0.001) and in group B (P3 <0.001) than C. EF had a significant difference among all groups (P <0.001). Early wave declaration time (DT) had a significant decline in group A (P2 = 0.049) and in group B (P3= 0.023) than C. Tissue doppler early velocity wave had a significant difference among all groups (P = 0.004). Tissue doppler early velocity wave had a significant decline in group A and B than C. (P2 = 0.038. P3 = 0.003).
Conclusions: AOR in HTN cases had a significant decline in DM cases compared with non-DM cases. In our results, glycaemic control didn’t play a significant role in aortic root.
Keywords: Aortic root diameter, Type 2 diabetes, HTN cases