Non-traumatic Subcapsular Hematoma of the Liver in a Patient under Rivaroxaban: A Rare Clinical Occurrence
B. Abdalani *
Department of Cardiology P37, Ibn Rochd University Hospital, Casablanca, Morocco.
M. Njie
Department of Cardiology P37, Ibn Rochd University Hospital, Casablanca, Morocco.
P. M. Mulendelé
Department of Cardiology P37, Ibn Rochd University Hospital, Casablanca, Morocco.
A. Zouad
Department of Cardiology P37, Ibn Rochd University Hospital, Casablanca, Morocco.
M. Haboub
Department of Cardiology P37, Ibn Rochd University Hospital, Casablanca, Morocco and Faculty of Medicine and Pharmacy, Hassan II University of Casablanca, Morocco.
G. M Benouna
Department of Cardiology P37, Ibn Rochd University Hospital, Casablanca, Morocco and Faculty of Medicine and Pharmacy, Hassan II University of Casablanca, Morocco.
A. Drighil
Department of Cardiology P37, Ibn Rochd University Hospital, Casablanca, Morocco and Faculty of Medicine and Pharmacy, Hassan II University of Casablanca, Morocco.
R. Habbal
Department of Cardiology P37, Ibn Rochd University Hospital, Casablanca, Morocco and Faculty of Medicine and Pharmacy, Hassan II University of Casablanca, Morocco and Faculty of Medicine, Cheikh Khalifa International University of Casablanca, Morocco.
*Author to whom correspondence should be addressed.
Abstract
Direct oral anticoagulants are used in the management and prophylaxis of venous thromboembolism (VTE) and other thrombotic diseases including non-valvular atrial fibrillation. The most serious complication of DOAC agents is bleeding, dominated by gastrointestinal hemorrhages, even if the bleeding risk is much rarer compared to VKA therapy. DOACs are sometimes linked to hepatotoxicity which can sometimes lead to severe hepatocellular insufficiency and also to non-hemorrhagic gastrointestinal disorders. We present a rare clinical entity of a spontaneous subcapsular hematoma of the liver in patient diagnosed with thrombosis of the right internal jugular vein treated with rivaroxaban, undergoing chemotherapy and hormonotherapy after surgery for breast cancer. The diagnosis was confirmed by imagery (abdominal CT scan) after clinical manifestation of an onset pain at the right hypochondrium of the abdomen. Conservative treatment was used in the patient with close follow up after hospital discharge.
Keywords: Hematoma, oral anticoagulants, rivaroxaban